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CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease
(Aging Cell, 2019-08)
CpG-related single nucleotide polymorphisms (CGS) have the potential to perturb DNA methylation; however, their effects on Alzheimer disease (AD) risk have not been evaluated systematically. We conducted a genome-wide ...
Low plasma adropin concentrations increase risks of weight gain and metabolic dysregulation in response to a high-sugar diet in male nonhuman primates
(JOURNAL OF BIOLOGICAL CHEMISTRY, 2019-06-21)
Mouse studies linking adropin, a peptide hormone encoded by the energy homeostasis-associated (ENHO) gene, to biological clocks and to glucose and lipid metabolism suggest a potential therapeutic target for managing diseases ...