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Progression and Pathology of Traumatic Optic Neuropathy From Repeated Primary Blast Exposure
(FRONTIERS IN NEUROSCIENCE, 2019-07-11)
Indirect traumatic optic neuropathy (ITON) is a condition that is often associated with traumatic brain injury and can result in significant vision loss due to degeneration of retinal ganglion cell (RGC) axons at the time ...
Galantamine protects against synaptic, axonal, and vision deficits in experimental neurotrauma
(Neurobiology of Disease, 2020-02)
Our goal was to investigate the neuroprotective effects of galantamine in a mouse model of blast-induced indirect traumatic optic neuropathy (bITON). Galantamine is an FDA-approved acetylcholinesterase inhibitor used to ...
Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis
(ELIFE, 2022-12-02)
An important question in organogenesis is how tissue-specific transcription factors interact with signaling pathways. In some cases, transcription factors define the context for how signaling pathways elicit tissue- or ...