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GPED Newsletter, 2007
GPED Newsletter, 2010
Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy
(Cell Reports, 2020-02-11)
The reliance of many cancers on aerobic glycolysis has stimulated efforts to develop lactate dehydrogenase (LDH) inhibitors. However, despite significant efforts, LDH inhibitors (LDHi) with sufficient specificity and in ...
First Pass Effect in Patients Treated With the Trevo Stent-Retriever: A TRACK Registry Study Analysis
(Frontiers in Neurology, 2020-02-18)
Background and Objective: The first pass effect (FPE; achieving complete recanalization with a single thrombectomy device pass) has been shown to be associated with higher rates of good clinical outcomes in patients with ...
Irritability and brain volume in adolescents: cross-sectional and longitudinal associations
(Social Cognitive and Affective Neuroscience, 2019-07)
Irritability is garnering increasing attention in psychiatric research as a transdiagnostic marker of both internalizing and externalizing disorders. These disorders often emerge during adolescence, highlighting the need ...
The Brickyard in 2020
The authors of this essay (David Furbish, Douglas Jerolmack and Rachel Glade) offer an updated view of the state of affairs in the brickyard described in B. K. Forscher’s popular 1963 allegorical letter to Science, “Chaos ...
The Young Brickmakers
In 2020, a young brickmaker (Kelsea Best) provides an update to B. K. Forscher's 1963 vision of the state of the scientific endeavor as a brickyard. As the brickyard becomes ever more chaotic, this essay calls on young ...