Browsing by Department "Chemistry"
Now showing items 41-60 of 346
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Boron Clusters as the Centerpiece of Advanced Liquid Crystals: Fundamental Chemistry and Properties (2011-04-06)Department: ChemistryLiquid crystals incorporating boron clusters are of interest for electro-optics, ion transport, and fundamental structure-property relationship studies. A liquid crystal is a fluid possessing orientational and positional ...
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(2009-10-05)Department: ChemistryThe 1,2-amino alcohol is a prevalent motif in natural products with biological activity. Many synthetic methods exist for the synthesis of 1,2-amino alcohols. Yet few are capable of setting both stereocenters in a single ...
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(2010-04-07)Department: ChemistryThe vicinal aminoalcohol moiety is a common structural motif in various groups of natural products, pharmaceuticals, ligands for metals, and chiral auxiliaries. A variety of synthetic molecules containing 1,2-aminoalcohols ...
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(2023-03-24)Department: ChemistryWith the rapid rise in global consumption of resources, research and development of new technologies has focused on alternative energy production as well as improving their performance to mitigate raw material consumption. ...
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(2019-07-22)Department: ChemistryThe metabotropic glutamate receptor 2/4 (mGlu2/4) heterodimer is a recently discovered receptor that displays unique pharmacology with respect to both mGlu2 and mGlu4 homodimeric receptors. Additionally, in vivo work has ...
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(2014-12-22)Department: ChemistryThe work presented here is the first of its kind where nanocrystal-based photovoltaics are characterized by directly imaging the electronic properties and correlating them to the structure of the sample. Through electron ...
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(2011-08-01)Department: ChemistryCharacterization of Post-Translationally Modified Peptides and Proteins Using Lanthanide-Based Labeling Strategies By Randi Gant-Branum Abstract: Numerous biological processes are regulated by the stoichiometry of protein ...
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(2018-11-27)Department: ChemistryAlkylating agents, once a weapon of war employed in World War I, are the oldest class of chemotherapeutic agents still used today, with applications in treating a wide array of cancers. Methylating agents, in particular, ...
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(2013-01-18)Department: ChemistryHerein we demonstrate the development and application of chiral bis(amidines) as organocatalysts in novel enantioselective transformations. A chiral, Brønsted base-catalyzed asymmetric alkylation of nitroalkanes is described ...
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(2009-12-03)Department: Chemistry1,2-Diamines form an important class of compounds, some members of which are valuable for their biological activity. In addition, chiral, non-racemic 1,2-diamines have emerged as an important class of ligands for ...
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(2016-08-04)Department: ChemistryThe proton is the smallest Lewis acid and has been utilized in nature by enzymes for catalysis and stereocontrol of a variety of reactions long before chemistry was pursued as the discipline it is today. This precedent ...
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(2006-08-07)Department: ChemistryChiral chromatography is a convenient method to obtain the pure enantiomers of a racemate and is also the most widely-used analytical technique to determine enantiomeric purity in the pharmaceutical industry. Seventeen new ...
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(2007-08-17)Department: ChemistryThe significance of being able to reliably establish the structure of chiral molecules is manifested through the recognition that different enantiomers and diastereomers of the same compound can have vastly different effects ...
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(2022-05-16)Department: ChemistryChirality permeates through modern science, from the spin of elementary particles to mechanisms underlying biological life processes. The amino acids and sugars from which proteins and nucleic acids are built exhibit ...
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(2016-04-01)Department: ChemistryRecent experimental studies have shown unexpected chiroptical response from some chiral surfactant molecules. In these cases, the magnitude of the specific optical rotation was seen to change as a function of surfactant ...
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(2006-10-30)Department: ChemistryParamyxovirus fusion glycoproteins mediate virus envelope and cell membrane fusion during viral entry. Fusion proteins are type I glycoproteins that exist as trimers with two 4-3 heptad repeat domains that form coiled coil ...
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(2005-03-09)Department: ChemistryThe combination of laser capture microdissection (LCM) and matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) for protein profiling from specific cells of interest within heterogeneous tissue is ...
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(2008-04-18)Department: ChemistryThe cyclooxygenase (COX) enzyme catalyzes the bis-dioxygenation and cyclization of arachidonic acid to form prostaglandin H2, the common precursor of bioactive prostaglandins. The genome codes two 60% sequence-identical ...
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(2016-04-07)Department: ChemistryComputational design of protein-ligand interfaces expands understanding of the basic forces involved in molecular recognition, and also contributes to the development of protein therapeutics. My dissertation research ...
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(2022-02-11)Department: ChemistryAntibodies (Abs) are proteins of the adaptive immune response that bind to and neutralize body-foreign particles (antigens). Specific binding to a wide variety of antigens is achieved by the tremendous variability inherent ...